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CAS No.: 10605-21-7

多菌灵 Catalog No. CSN20803

Synonyms: 多菌灵

Carbendazim is a widely used, broad-spectrum benzimidazole fungicide with potential antimitotic and antineoplastic activities, used to control plant diseases in cereals and fruits.

规格	价格	促销价格	库存	数量

400-920-2911

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实验方案

技术信息

生物活性

描述Carbendazim (CBZ) is a potent and orally active broad-spectrum benzimidazole fungicide and can be acts as a pesticide for fungal diseases research, such as Seproria, Fusarium and Sclerotina. Oral administrations with CBZ at 100 and 500 mg/kg body weight for 28 days induced hepatic lipid metabolism disorder which was characterized by significant increases of hepatic lipid accumulation and triglyceride (TG) levels in mice. Moreover, the increase in serum IL-1β and IL-6 levels by the treatment of CBZ indicated the occurring of inflammation^[1]. All tested carbendazim and astaxanthin combinations increased the anti-proliferative effect of Carb treatment alone and increased the G2/M phase cell cycle arrest compared to the DMSO-treated control. Astaxanthin and carbendazim co-treatment enhances the anti-proliferative effect of carbendazim as a single agent, while alleviating the carbendazim treatment-associated ROS production in MCF-7 cells^[2].
参考文献

[1] Jin Y, Zeng Z, Wu Y, Zhang S, Fu Z. Oral Exposure of Mice to Carbendazim Induces Hepatic Lipid Metabolism Disorder and Gut Microbiota Dysbiosis. Toxicol Sci. 2015 Sep;147(1):116-26
[2] Atalay PB, Kuku G, Tuna BG. Effects of carbendazim and astaxanthin co-treatment on the proliferation of MCF-7 breast cancer cells. In Vitro Cell Dev Biol Anim. 2019 Feb;55(2):113-119

实验方案

计算器摩尔计算器总药量计算器工作液计算器
储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 5.2305 mL
- 26.1524 mL
- 52.3049 mL
- 5 mM
- 1.0461 mL
- 5.2305 mL
- 10.4610 mL
- 10 mM
- 0.5230 mL
- 2.6152 mL
- 5.2305 mL

技术信息

CAS号

10605-21-7

储存条件

粉末: Sealed in dry,Room Temperature

液体: -20°C:3-6 月 -80°C:12月

分子式

C9H9N3O2

运输

蓝冰

分子量

191.19

别名

多菌灵

溶解度

DMSO	16.0 mg/mL (83.7 mM)
Water	Insoluble
Ethanol	Insoluble

动物实验配方

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